A senior lecturer in occupational health and acting head of the School of Public Health at the University of Botswana. He is recognized as a leading human rights activist in southern Africa.
Matchaba-Hove is a member of the steering committee of the World Movement for Democracy, an ex-officio member of the management committee of the African Democracy Forum, and an inaugural board member of the Southern Africa Trust.
He has also served as a member of the Joint Health Planning Committee of the Ministry of Health and as chair of the University of Zimbabwe's Department of Community Medicine. From 1992 to 1999, he was the inaugural chair of the Zimbabwe Human Rights Association.
From 2001 to 2007, Matchaba-Hove served as the national chair of the Zimbabwe Election Support Network, which engaged in voter education, election monitoring, advocacy, and research on electoral issues. Matchaba-Hove has an MSc in occupational medicine from the University of London. He received his BA in medicine and surgery from the University of Zimbabwe.